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Publications:
2018
- Simultaneous surface display and cargo loading of encapsulin nanocompartments and their use for rational vaccine design
Authors: Lagoutte P, Mignon C, Stadthagen G, Potisopon S, Donnat S, Mast J, Lugari A, Werle B.
- Codon harmonization – going beyond the speed limit for protein expression
Authors: Mignon C, Mariano N, Stadthagen G, Lugari A, Lagoutte P, Donnat S, Chenavas S, Perot C, Sodoyer R, Werle B.
Journal: FEBS Press
2017
- The human gut microbiome as source of innovation for health: Which physiological and therapeutic outcomes could we expect?
Authors: Doré J, Multon MC, Béhier JM, Affagard H, Andremont A, Barthélémy P, Batitsa R, Bonneville M, Bonny C, Boyaval G, Chamaillard M, Chevalier MP, Cordaillat-Simmons M, Cournarie F, Diaz I, Guillaume E, Guyard C, Jouvin-Marche E, Martin FP, Petiteau D.
Review: Therapie, Elsevier
- Modulation of estrogen related receptor alpha activity by the kinesin KIF17.
Authors: Seneviratne APB, Turan Z, Hermant A, Lecine P, Smith WO, Borg JP, Jaulin F, Kreitzer G.
Journal: Oncotarget
- Membrane-Active Properties of an Amphitropic Peptide from the CyaA Toxin Translocation Region
Authors: Voegele A, Subrini O, Sapay N, Ladant D, Chenal A.
Journal: Toxins (Basel).
- Lactobacillus paracasei feeding improves immune control of influenza infection in mice
Authors: Belkacem N, Serafini N, Wheeler R, Derrien M, Boucinha L, Couesnon A, Cerf-Bensussan N, Gomperts Boneca I, Di Santo JP, Taha MK, Bourdet-Sicard R.
Journal: PLoS One.
- Signal management in pharmacovigilance and human risk assessment of CpG 7909, integrating embryo-fetal and post-natal developmental toxicity studies in rats and rabbits
Authors: Delannois F, Planty C, Giordano G, Destexhe E, Stanislaus D, Da Silva FT, Stegmann JU, Thacker K, Reynaud L, Garçon N, Segal L.
Journal: Reprod Toxicol.
- Cellular and molecular synergy in AS01-adjuvanted vaccines results in an early IFNγ response promoting vaccine immunogenicity
Authors: Coccia M, Collignon C, Hervé C, Chalon A, Welsby I, Detienne S, Helden MJV, Dutta S, Genito CJ, Waters NC, Deun KV, Smilde AK, Berg RAVD, Franco D, Bourguignon P, Morel S, Garçon N, Lambrecht BN, Goriely S, Most RV, Didierlaurent AM.
Journal: NPJ Vaccines
- Different Adjuvants Induce Common Innate Pathways That Are Associated with Enhanced Adaptive Responses against a Model Antigen in Humans
Authors: Burny W, Callegaro A, Bechtold V, Clement F, Delhaye S, Fissette L, Janssens M, Leroux-Roels G, Marchant A, van den Berg R. A, Garçon N, van der Most R and Didierlaurent Arnaud M. On Behalf of the ECR-002 Study Group
Journal: Frontiers in Immunology
- The REAnimation Low Immune Status Markers (REALISM) project: a protocol for broad characterisation and follow-up of injury-induced immunosuppression in intensive care unit (ICU) critically ill patients
Authors: Rol ML, Venet F, Rimmele T, Moucadel V, Cortez P, Quemeneur L, Gardiner D, Griffiths A, Pachot A, Textoris J, Monneret G; REALISM study group.
Journal: BMJ Open
- Intramuscularly administered herpes zoster subunit vaccine has no effects on fertility, pre- and post-natal development in Sprague-Dawley rats
Authors: Segal L, Thacker K, Fochesato M, Giordano G, Garçon N, Destexhe E.
Journal: Reprod Toxicol.
- Type I interferon-mediated autoinflammation due to DNase II deficiency
Authors: Rodero M.P , Tesser A, Bartok E, Rice G. I. , Della Mina E , Depp M, Beitz B, Bondet V, Cagnard N, Duffy D, Dussiot M, Frémond M-L, Gattorno M, Guillem F, Kitabayashi N, Porcheray F, Rieux-Laucat F, Seabra L, Uggenti C, Volpi S, Zeef L.A.H , Alyanakian M-A, Beltrand J, Bianco A-M, Boddaert N, Brouzes C, Candon S, Caorsi R, Charbit M, Fabre M, Faletra F, Girard M, Harroche A, Hartmann E, Lasne D, Marcuzzi A, Neven B, Nitschke P, Pascreau T, Pastore S, Picard C, Picco P,Piscianz E, Polak M, Quartier P, Rabant M, Stocco G, Taddio A, Uettwiller F, Valencic E, Vozzi D, Hartmann G, Barchet W, Hermine O, Bader-Meunier B, Tommasini A & Crow Y.J
Journal: Nature Communication
- Respiratory Syncytial Virus Infects Regulatory B Cells in Human Neonates via Chemokine Receptor CX3CR1 and Promotes Lung Disease Severity
Authors: Zhivaki D, Lemoine S, Lim A, Morva A, Vidalain P-O, Schandene L, Casartelli N, Rameix-Welti M-A, Herve P-L , Dériaud E, Beitz B, Ripaux-Lefevre M, Miatello J, Lemercier B, Lorin V, Descamps D, Fix J, Eléouët J-F et Riffault S , Schwartz O, Porcheray F, Mascart F, Mouquet H, Zhang X, Tissières P and Lo-Man R.
Journal: Immunity
2016
- Chapitre: Les vaccins ou deux siècles de biotechnologies
Authors: Sodoyer R, Drouet E, Werle B
Book: Les biotechnologies en santé tome1.
- Non-conventional expression systems for the production of vaccine proteins and immunotherapeutic molecules
Authors: Legastelois I, Buffin S, Peubez I, Mignon C, Sodoyer R,Werle B
Review: Hum Vaccin & immunotherapeutics
- From discovery to licensure, the Adjuvant System story
Authors: Garçon N, Di Pasquale A.
Journal: Hum Vaccin Immunother.
- Vaccine safety evaluation: Practical aspects in assessing benefits and risks
Authors: Di Pasquale A, Bonanni P, Garçon N, Stanberry LR, El-Hodhod M, Tavares Da Silva F.
Journal: Vaccine
- Vaccine provision: Delivering sustained & widespread use
Authors: Preiss S, Garçon N, Cunningham AL, Strugnell R, Friedland LR.
Journal: Vaccine
- Vaccine development: From concept to early clinical testing
Authors: Cunningham AL, Garçon N, Leo O, Friedland LR, Strugnell R, Laupèze B, Doherty M, Stern P.
Journal: Vaccine
- Zika antiviral chemotherapy: identification of drugs and promising starting points for drug discovery from an FDA-approved library
Authors: Pascoalino B.S, Courtemanche G, Cordeiro M.T, Gil L. H. V. G. , Freitas-Junior L
Journal: F1000Research
- Impact of adjuvants on CD4(+) T cell and B cell responses to a protein antigen vaccine: Results from a phase II, randomized, multicenter trial
Authors: Leroux-Roels G, Marchant A, Levy J, Van Damme P, Schwarz TF, Horsmans Y, Jilg W, Kremsner PG, Haelterman E, Clément F, Gabor JJ, Esen M, Hens A, Carletti I, Fissette L, Tavares Da Silva F, Burny W, Janssens M, Moris P, Didierlaurent AM, Van Der Most R, Garçon N, Van Belle P, Van Mechelen M.
Journal: Clin Immunol.
- Reducing hypoxia and inflammation during invasive pulmonary aspergillosis by targeting the Interleukin-1 receptor
Authors: Gresnigt M.S. , Rekiki A, Rasid O, Savers A, Jouvion G, Dannaoui E, Parlato M, Fitting C, Brock M, Cavaillon J-M, van de Veerdonk F. L. & Ibrahim-Granet O
Journal: Nature Scientific Reports
- Chapter 5: Hydrophilic Interaction Liquid Chromatography (HILIC) and Perfluorinated Stationary Phases, pp. 149-184
Authors: Cristina C. JACOB
Book: Fast Liquid Chromatography – Mass Spectrometry Methods in Food and Environmental Analysis (Imperial College Press)
- Legionella CRISPR-Cas reveals a recurrent challenge to the pathogen
Authors: Rao C, Guyard C, Pelaz C, Wasserscheid J, Bondy-Denomy J, Dewar K, Ensminger AW.
Journal: Cell Microbiol.
- Scalable chromatography-based purification of virus-like particle carrier for epitope based Influenza A vaccine produced in Escherichia coli
Authors: Lagoutte P, Mignon C, Donnat S, Stadthagen G, Mast J, Sodoyer R, Lugari A and Werle B
Journal: J. Virol. Methods
2015
- Antibiotic free selection in Biotherapeutics
Authors: Mignon C. , Sodoyer R. , Werle B.
Journal: Antibiotic free selection in Biotherapeutics: Now and Forever, Pathogens
- A FACS-optimized screen identifies regulators of genome stability in Candida albicans
Authors: Loll-Krippleber R, Feri A, Nguyen M, Maufrais C, Yansouni J, d'Enfert C, Legrand M
Journal: Eukaryot Cell.
POSTERS:
2017:
- Combinatorial design for random molecular cloning and screening of high yield expression vectors
Authors: Mariano N, Mignon C, Stadthagen Gomez G, Donnat S, Lagoutte P, Werle B
Conference: Recombinant Protein Production, 23-25 april Dubrovnik Croatie
- BIOSPECIMENS v1.5: a web platform to facilitate collaborative research on infectious diseases
Authors: Louis K, Rimbault B, Delestre C, Mouscaz Y, Albrieux M, Boisse C, Villet R, Boissy G
Conference: JOBIM, 2017
2016
- Evaluation of integrative approaches for the analysis of multi_omics data
Authors: Novoloaca A, Reynier F, Becker J
JOBIM, 2016
- Protein sequence recoding, codon usage bias on the bench
Authors: Mariano N, Mignon C, Chenavas S, Stadthagen G, Lugari A, Perot C., Donnat S, Lagoutte P, Diot F, Sodoyer R, Werle B
Conference: PEGS Boston
- Met-SAMoA (Metabolic Screening of Antimicrobial Mode of Action) Development of an integrated NMR/MS metabolomics approach for the determination of the novelty of new antimicrobials mechanisms of action based on their metabolic signature
Authors: Bunescu A, Ouattara D.A, Meniche X, Billaut E, Boisse C, Tambosco J and Bequet F
Conference: ECCMID 2016, Amsterdam, NL
- Development of an improved protocol for lipid analysis based on heat inactivation of enzymes
Authors: Meniche X, Ouattara D.A, Hennig K, Sköld K, Boren M, Elias Y, Biliaut E, Bogeat P, Boisse C, Peltier M, Jacob C, Bunescu A, Bequet F
Conference: IPID MAPS Annual Meeting 2016, La Jolla, US
- Prevention of metabolite change due to enzymatic post-sample activity using heat based enzyme inactivation
Authors: Bunescu A, Ouattara D. A, Sköld K, Boren M, Biliaut E, Hennig K ,Bogeat P, Boisse C, Peltier M, Meniche X, Jacob C, Bequet F
Conference: 5th International Conference and Exhibition on Metabolomics, Osaka, Japan
- The bioinformatics timeline of the data integration in BIOASTER
Authors: Mouscaz Y, Cauchard A, Malinovic A, Picandet L, Sapay N, Veyre P and Boissy G
Conference: JeBiF Workshop @ JOBIM 2016 Lyon
- Validation of methods to characterize and monitor injury-induced immune deficiency in severe intensive care unit patients
Authors: Rol M.L, Moucadel V, Cerrato E, Riffaud C, Gallet-Gorius E, Portier A, Demaret J, Tabone O, Malcus C, Rimmele T, Monneret G, Textoris J, Venet F, On behalf of the Realism Study Group
Conference: Congres ESID Barcelona
2015
- BIOSPECIMEN: a web platform developed to facilitate research on infectious diseases & microbiota
Authors: Louis K, Rimbault B, Gaillard C, Costaz L, Guyard C, Khlebnikov A and Troesch A
Conference: CCO XXXIV European Culture Collections as tools in research and biotechnology. Paris
- Comparative Analysis – A Balb/c Mice Core Gut Microbiome?
Authors: Boucinha L, Reynier F, Schwarzer M, Leulier F, van Hijum S
Conference: The Human Microbiome, EMBL conference, Heidelberg, Germany, June 2015
- Insight into the Protein and Expression Systems Engineering unit of Bioaster, a technology institute specialized in infectious diseases and microbiology
Authors: Donnat S, Lagoutte P, Lugari A, Mignon C, Sodoyer R, Stadthagen G and Werle B
Conference: French Brazilian Biomedical Innovation Forum, San Paoulo Instituit Butantan
- Controlled ultrasound cavitation for DNA delivery into bacteria and yeast/ Award for best poster
Authors: Stadthagen G, Mignon C, Mestas J-L, Donnat S, Poncet E, Sodoyer R, Lafon C, Werle B
Conference: International Conference of Synthetic Biology, Houston, Sept 2015
- Fast protein liquid chromatography based purification of MS2 bacteriophage virus-like particles
Authors: Lagoutte P, Mignon C, Donnat S, Mast J, Lugari A and Werle B
Conference: Word vaccine congres Europe, Madrid, 9 au 12 novembre 2015
- A new animal facility in Lyon Gerland area to explore microbiome
Authors: Darnaud M, Peltier M, Tamellini A et al
Conference: 8ème Journée Scientifique de la SFR Biosciences, Lyon
- BIOASTER: Animal models and imaging competencies to improve chlamydial studies
Authors: Rekiki A, Darnaud M, Gaudin A , Peltier M, Bogeat P, Tamellini A
Conference: European meeting on animal chlamydiosis
- Multi-omics data integration platform in public-private partnership
Authors: Sapay N, Veyre P, Le Carrour T, Cauchard A, Garnier J
Conference: JOBIM, Clermont-Ferrand
- Evaluation of heat stabilization for the conservation of biological samples as an approach for metabolomics: a 1H-NMR/LC-MS metabolite profiling study
Authors: Bequet F, Bunescu A, Ouattara D.A, Meniche X, Da Costa Jacob C, Billiaut E, Bogeat P, Gaillard C, Peltier M, Sköld K, Boren M, Tamellini A, Guyard C, Troesch A
Conference: Metabolomics Conference 2015 - San Francisco (US)