• Codon harmonization – going beyond the speed limit for protein expression

Authors: Mignon C, Mariano N, Stadthagen G, Lugari A, Lagoutte P, Donnat S, Chenavas S, Perot C, Sodoyer R, Werle B.

Journal: FEBS Press

2017

• The human gut microbiome as source of innovation for health: Which physiological and therapeutic outcomes could we expect?

Authors: Doré J, Multon MC, Béhier JM, Affagard H, Andremont A, Barthélémy P, Batitsa R, Bonneville M, Bonny C, Boyaval G, Chamaillard M, Chevalier MP, Cordaillat-Simmons M, Cournarie F, Diaz I, Guillaume E, Guyard C, Jouvin-Marche E, Martin FP, Petiteau D.

Review: Therapie, Elsevier

• Modulation of estrogen related receptor alpha activity by the kinesin KIF17.

Authors: Seneviratne APB, Turan Z, Hermant A, Lecine P, Smith WO, Borg JP, Jaulin F, Kreitzer G.

Journal: Oncotarget

• Membrane-Active Properties of an Amphitropic Peptide from the CyaA Toxin Translocation Region

Authors: Voegele A, Subrini O, Sapay N, Ladant D, Chenal A.

Journal: Toxins (Basel).

• Lactobacillus paracasei feeding improves immune control of influenza infection in mice

Authors: Belkacem N, Serafini N, Wheeler R, Derrien M, Boucinha L, Couesnon A, Cerf-Bensussan N, Gomperts Boneca I, Di Santo JP, Taha MK, Bourdet-Sicard R.

Journal: PLoS One.

• Signal management in pharmacovigilance and human risk assessment of CpG 7909, integrating embryo-fetal and post-natal developmental toxicity studies in rats and rabbits

Authors: Delannois F, Planty C, Giordano G, Destexhe E, Stanislaus D, Da Silva FT, Stegmann JU, Thacker K, Reynaud L, Garçon N, Segal L.

Journal: Reprod Toxicol.

• Cellular and molecular synergy in AS01-adjuvanted vaccines results in an early IFNγ response promoting vaccine immunogenicity

Authors: Coccia M, Collignon C, Hervé C, Chalon A, Welsby I, Detienne S, Helden MJV, Dutta S, Genito CJ, Waters NC, Deun KV, Smilde AK, Berg RAVD, Franco D, Bourguignon P, Morel S, Garçon N, Lambrecht BN, Goriely S, Most RV, Didierlaurent AM.

Journal: NPJ Vaccines

• Different Adjuvants Induce Common Innate Pathways That Are Associated with Enhanced Adaptive Responses against a Model Antigen in Humans

Authors:  Burny W, Callegaro A, Bechtold V, Clement F, Delhaye S, Fissette L, Janssens M,  Leroux-Roels G,  Marchant A, van den Berg R. A, Garçon N, van der Most R and Didierlaurent Arnaud M. On Behalf of the ECR-002 Study Group

Journal: Frontiers in Immunology

• The REAnimation Low Immune Status Markers (REALISM) project: a protocol for broad characterisation and follow-up of injury-induced immunosuppression in intensive care unit (ICU) critically ill patients

Authors: Rol ML, Venet F, Rimmele T, Moucadel V, Cortez P, Quemeneur L, Gardiner D, Griffiths A, Pachot A, Textoris J, Monneret G; REALISM study group.

Journal: BMJ Open

• Intramuscularly administered herpes zoster subunit vaccine has no effects on fertility, pre- and post-natal development in Sprague-Dawley rats

Authors: Segal L, Thacker K, Fochesato M, Giordano G, Garçon N, Destexhe E.

Journal: Reprod Toxicol.

• Type I interferon-mediated autoinflammation due to DNase II deficiency

Authors: Rodero M.P , Tesser A, Bartok E, Rice G. I. , Della Mina E , Depp M, Beitz B, Bondet V, Cagnard N, Duffy D, Dussiot M, Frémond M-L, Gattorno M, Guillem F, Kitabayashi N, Porcheray F, Rieux-Laucat F, Seabra L, Uggenti C, Volpi S,  Zeef L.A.H , Alyanakian M-A, Beltrand J,  Bianco A-M, Boddaert N, Brouzes C, Candon S, Caorsi R,  Charbit M, Fabre M, Faletra F, Girard M, Harroche A, Hartmann E, Lasne D, Marcuzzi A, Neven B, Nitschke P, Pascreau T, Pastore S, Picard C, Picco P,Piscianz E, Polak M, Quartier P, Rabant M, Stocco G, Taddio A, Uettwiller F, Valencic E, Vozzi D, Hartmann G, Barchet W, Hermine O, Bader-Meunier B,  Tommasini A & Crow Y.J

Journal: Nature Communication

• Respiratory Syncytial Virus Infects Regulatory B Cells in Human Neonates via Chemokine Receptor CX3CR1 and Promotes Lung Disease Severity

Authors: Zhivaki D, Lemoine S, Lim A, Morva A, Vidalain P-O, Schandene L, Casartelli N, Rameix-Welti M-A, Herve P-L , Dériaud E, Beitz B, Ripaux-Lefevre M,  Miatello J, Lemercier B, Lorin V, Descamps D, Fix J, Eléouët J-F et  Riffault S , Schwartz O, Porcheray F, Mascart F, Mouquet H, Zhang X, Tissières P and Lo-Man R.

Journal: Immunity

2016

• Chapitre: Les vaccins ou deux siècles de biotechnologies

Authors: Sodoyer R, Drouet E, Werle B

Book: Les biotechnologies en santé tome1.

• Non-conventional expression systems for the production of vaccine proteins and immunotherapeutic molecules

Authors: Legastelois I, Buffin S, Peubez I, Mignon C, Sodoyer R,Werle B

Review: Hum Vaccin & immunotherapeutics

• From discovery to licensure, the Adjuvant System story

Authors: Garçon N, Di Pasquale A.

Journal: Hum Vaccin Immunother.

• Vaccine safety evaluation: Practical aspects in assessing benefits and risks

Authors: Di Pasquale A, Bonanni P, Garçon N, Stanberry LR, El-Hodhod M, Tavares Da Silva F.

Journal: Vaccine

• Vaccine provision: Delivering sustained & widespread use

Authors: Preiss S, Garçon N, Cunningham AL, Strugnell R, Friedland LR.

Journal: Vaccine

• Vaccine development: From concept to early clinical testing

Authors: Cunningham AL, Garçon N, Leo O, Friedland LR, Strugnell R, Laupèze B, Doherty M, Stern P.

Journal: Vaccine

• Zika antiviral chemotherapy: identification of drugs and promising starting points for drug discovery from an FDA-approved library

Authors: Pascoalino B.S, Courtemanche G, Cordeiro M.T, Gil L. H. V. G. , Freitas-Junior L

Journal: F1000Research

• Impact of adjuvants on CD4(+) T cell and B cell responses to a protein antigen vaccine: Results from a phase II, randomized, multicenter trial

Authors: Leroux-Roels G, Marchant A, Levy J, Van Damme P, Schwarz TF, Horsmans Y, Jilg W, Kremsner PG, Haelterman E, Clément F, Gabor JJ, Esen M, Hens A, Carletti I, Fissette L, Tavares Da Silva F, Burny W, Janssens M, Moris P, Didierlaurent AM, Van Der Most R, Garçon N, Van Belle P, Van Mechelen M.

Journal: Clin Immunol.

• Reducing hypoxia and inflammation during invasive pulmonary aspergillosis by targeting the Interleukin-1 receptor

Authors: Gresnigt M.S. , Rekiki A, Rasid O, Savers A, Jouvion G, Dannaoui E, Parlato M, Fitting C, Brock M, Cavaillon J-M,  van de Veerdonk F. L. & Ibrahim-Granet O

Journal: Nature Scientific Reports

• Chapter 5: Hydrophilic Interaction Liquid Chromatography (HILIC) and Perfluorinated Stationary Phases, pp. 149-184

Authors: Cristina C. JACOB

Book: Fast Liquid Chromatography – Mass Spectrometry Methods in Food and Environmental Analysis (Imperial College Press)

• Legionella CRISPR-Cas reveals a recurrent challenge to the pathogen

Authors: Rao C, Guyard C, Pelaz C, Wasserscheid J, Bondy-Denomy J, Dewar K, Ensminger AW.

Journal: Cell Microbiol.

• Scalable chromatography-based purification of virus-like particle carrier for epitope based Influenza A vaccine produced in Escherichia coli

Authors: Lagoutte P, Mignon C, Donnat S, Stadthagen G, Mast J, Sodoyer R, Lugari A and Werle B

Journal: J. Virol. Methods

2015

• Antibiotic free selection in Biotherapeutics

Authors: Mignon C. , Sodoyer R. , Werle B.

Journal: Antibiotic free selection in Biotherapeutics: Now and Forever, Pathogens

• A FACS-optimized screen identifies regulators of genome stability in Candida albicans

Authors: Loll-Krippleber R, Feri A, Nguyen M, Maufrais C, Yansouni J, d'Enfert C, Legrand M

Journal: Eukaryot Cell.

POSTERS:

2017:

• Combinatorial design for random molecular cloning and screening of high yield expression vectors

Authors: Mariano N, Mignon C, Stadthagen Gomez G, Donnat S, Lagoutte P, Werle B

Conference: Recombinant Protein Production, 23-25 april Dubrovnik Croatie

• BIOSPECIMENS v1.5: a web platform to facilitate collaborative research on infectious diseases

Authors: Louis K, Rimbault B, Delestre C, Mouscaz Y, Albrieux M, Boisse C, Villet R, Boissy G

Conference: JOBIM, 2017

2016

• Evaluation of integrative approaches for the analysis of multi_omics data

Authors: Novoloaca A, Reynier F, Becker J

JOBIM, 2016

• Protein sequence recoding, codon usage bias on the bench

Authors: Mariano N, Mignon C, Chenavas S, Stadthagen G, Lugari A, Perot C., Donnat S, Lagoutte P, Diot F, Sodoyer R, Werle B

Conference: PEGS Boston

• Met-SAMoA (Metabolic Screening of Antimicrobial Mode of Action) Development of an integrated NMR/MS metabolomics approach for the determination of the novelty of new antimicrobials mechanisms of action based on their metabolic signature

Authors: Bunescu A, Ouattara D.A, Meniche X, Billaut E, Boisse C, Tambosco J and Bequet F

Conference: ECCMID 2016, Amsterdam, NL

• Development of an improved protocol for lipid analysis based on heat inactivation of enzymes

Authors: Meniche X, Ouattara D.A, Hennig K, Sköld K, Boren M, Elias Y, Biliaut E, Bogeat P, Boisse C, Peltier M, Jacob C, Bunescu A, Bequet F

Conference: IPID MAPS Annual Meeting 2016, La Jolla, US

• Prevention of metabolite change due to enzymatic post-sample activity using heat based enzyme inactivation

Authors: Bunescu A, Ouattara D. A, Sköld K, Boren M, Biliaut E, Hennig K ,Bogeat P,  Boisse C, Peltier M, Meniche X, Jacob C, Bequet F

Conference: 5th International Conference and Exhibition on Metabolomics, Osaka, Japan

• The bioinformatics timeline of the data integration in BIOASTER

Authors: Mouscaz Y, Cauchard A, Malinovic A, Picandet L, Sapay N, Veyre P and Boissy G

Conference: JeBiF Workshop @ JOBIM 2016 Lyon

• Validation of methods to characterize and monitor injury-induced immune deficiency in severe intensive care unit patients

Authors: Rol M.L, Moucadel V, Cerrato E, Riffaud C, Gallet-Gorius E, Portier A, Demaret J, Tabone O, Malcus C, Rimmele T, Monneret G, Textoris J, Venet F, On behalf of the Realism Study Group

Conference: Congres ESID Barcelona

2015

• BIOSPECIMEN: a web platform developed to facilitate research on infectious diseases & microbiota

Authors: Louis K, Rimbault B, Gaillard C, Costaz L, Guyard C, Khlebnikov A and Troesch A

Conference: CCO XXXIV European Culture Collections as tools in research and biotechnology. Paris

• Comparative Analysis – A Balb/c Mice Core Gut Microbiome?

Authors: Boucinha L, Reynier F, Schwarzer M, Leulier F, van Hijum S

Conference: The Human Microbiome, EMBL conference, Heidelberg, Germany, June 2015

• Insight into the Protein and Expression Systems Engineering unit of Bioaster, a technology institute specialized in infectious diseases and microbiology

Authors: Donnat S, Lagoutte P, Lugari A, Mignon C, Sodoyer R,  Stadthagen G and Werle B

Conference: French Brazilian Biomedical Innovation Forum, San Paoulo Instituit Butantan

• Controlled ultrasound cavitation for DNA delivery into bacteria and yeast/ Award for best poster

Authors: Stadthagen G,  Mignon C, Mestas J-L, Donnat S, Poncet E, Sodoyer R, Lafon C, Werle B

Conference: International Conference of Synthetic Biology, Houston, Sept 2015

• Fast protein liquid chromatography based purification of MS2 bacteriophage virus-like particles

Authors: Lagoutte P, Mignon C, Donnat S, Mast J, Lugari A and Werle B

Conference: Word vaccine congres Europe, Madrid, 9 au 12 novembre 2015

• A new animal facility in Lyon Gerland area to explore microbiome

Authors: Darnaud M, Peltier M,  Tamellini A et al

Conference: 8ème Journée Scientifique de la SFR Biosciences, Lyon

• BIOASTER: Animal models and imaging competencies to improve chlamydial studies

Authors: Rekiki A, Darnaud M, Gaudin A , Peltier M, Bogeat P, Tamellini A

Conference: European meeting on animal chlamydiosis

• Multi-omics data integration platform in public-private partnership

Authors: Sapay N, Veyre P, Le Carrour T, Cauchard A, Garnier J

Conference: JOBIM, Clermont-Ferrand

• Evaluation of heat stabilization for the conservation of biological samples as an approach for metabolomics: a 1H-NMR/LC-MS metabolite profiling study

Authors: Bequet F, Bunescu A, Ouattara D.A, Meniche X, Da Costa Jacob C, Billiaut E, Bogeat P, Gaillard C, Peltier M, Sköld K,  Boren M,  Tamellini A, Guyard C,  Troesch A

Conference: Metabolomics Conference 2015 - San Francisco (US)