Our Mission

Analyse
  • Developing advanced and innovative technologies to  accelerate your microbiological research.
  • Delivering high-level scientific, clinical and technological solutions to solve complex research questions for animal and human health.

EXPERTISE

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Access to clinical samples

We coordinate all aspect of new clinical study development. Our duty is to provide our partner with the high standard (ISO 9001) of clinical material. Therefore, we support your scientific activity to find new solution in microbiology and infectious diseases.

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Microorganism identification

The cutting-edge technological platform allowing isolation and characterization of microbiological strains of interest from complex biological samples. In order to increase the value of microbiological collections, we developed a series of diagnostic tests to exploring specific phenotypic traits such as antibiotic resistance, Biofilm formation, quorum sensing, bacteriocins production, etc. Our laboratories are specialized to work in aerobic, anaerobic environment and with highly pathogenic microorganisms – BSL-3 facility

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Molecular engineering

Multidisciplinary players to develop innovative approaches from designing to producing of the complex molecules of your clinical needs. We have designed advance technologies e.g. for alternative antibodies production; enrich lipoprotein production or capsulate drug delivery system. Our in-house capabilities will help you in improvement of new clinical strategies such as design new vaccine, novel diagnostic tolls or drug delivery system.

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Integrated biofilm platform

Integrated biofilm platform (Biofilm-ID) for high throughput biofilm investigation. Our system contains the chain of static and dynamic biofilm models in order to investigate a biofilm formation, prevention and eradication. This platform is suited for biofilm microscopic analysis, multiomic studies of mono- or multispecies biofilms.

DEVELOPED TECHNOLOGIES

  • BindIT – Fast de novo generation of binders

  • NanoCage – Versatile vectorization system

  • Biofilm

  • Anoxic Platform

Equipment

ADVANCED MICROBIOLOGY

Advanced Microbiology

NETWORK & PARTNERSHIP

Publications:

  • Sorting and cultivation of Faecalibacterium prausnitzii from fecal samples using flow cytometry in anaerobic conditions
    Bellais S, et al. bioRxiv 2020 ePuB DOI 10.1101/2020.03.25.007047
  • Characterization and analytical validation of a new antigenic rapid diagnostic test for Ebola virus disease detection.
    Couturier C, et al. PLoS Negl Trop Dis. 2020;14(1):e0007965. DOI 10.1371/journal.pntd.0007965
  • Combination of ribosome display and next generation sequencing as a powerful method for identification of affibody binders against β-lactamase CTX-M15.
    Lagoutte P, et al. N Biotechnol. 2019;50:60-69 DOI 10.1016/j.nbt.2019.01.004
  • A steam-based method to investigate biofilm.
    Tasse J, et al. Sci Rep. 2018;8(1):13040 DOI 10.1038/s41598-018-31437-y
  • Codon harmonization – going beyond the speed limit for protein expression.
    Mignon C, et al. FEBS Lett. 2018; 592(9):1554-1564 DOI 10.1002/1873-3468.13046
  • Simultaneous surface display and cargo loading of encapsulin nanocompartments and their use for rational vaccine design.
    Lagoutte P, et al. Vaccine. 2018 ;36(25):3622-3628 DOI 10.1016/j.vaccine.2018.05.034
  • Non-conventional expression systems for the production of vaccine proteins and immunotherapeutic molecules.
    Legastelois I, et al. Hum Vaccin Immunother. 2017;13(4):947-961 DOI 10.1080/21645515.2016.1260795
  • Scalable Chromatography-Based Purification of Virus-Like Particle Carrier for Epitope Based Influenza A Vaccine Produced in Escherichia coli.
    Lagoutte P, et al. J Virol Methods. 2016 Jun;232:8-11 DOI 10.1016/j.jviromet.2016.02.011
  • Antibiotic-Free Selection in Biotherapeutics: Now and Forever
    Mignon C, et al. Pathogens. 2015; 4(2): 157–181 DOI 10.3390%2Fpathogens4020157