Publications:

2019

Combination of ribosome display and next generation sequencing as a powerful method for identification of affibody binders against β-lactamase CTX-M15
Authors: Lagoutte P, Lugari A, Elie C, Potisopon S, Donnat S, Mignon C, Mariano N, Troesch A, Werle B, Stadthagen G.;
Journal: N Biotechnol. 2019 May 25;50:60-69

2018

Translocation and calmodulin-activation of the adenylate cyclase toxin (CyaA) of Bordetella pertussis
Authors: Voegele A, O’Brien DP, Subrini O, Sapay N, Cannella SE, Enguéné VYN, Hessel A, Karst J, Hourdel V, Perez ACS, Davi M, Veneziano R, Chopineau J, Vachette P, Durand D, Brier S, Ladant D, Chenal A.
Journal: Pathog Dis.
Metagenomics next generation sequencing reveals individual composition and dynamics of anelloviruses during autologous stem cell Transplant Recipient Management
Authors: Bal A, Sarkozy C, Josset L, Cheynet V, Oriol G, Becker J, Vilchez G, Sesques P, Mallet F, Pachot A, Morfin F, Lina B, Salles G, Reynier F, Trouillet-Assant S, Brengel-Pesce K.
Journal: Viruses
Simultaneous surface display and cargo loading of encapsulin nanocompartments and their use for rational vaccine design
Authors: Lagoutte P, Mignon C, Stadthagen G, Potisopon S, Donnat S, Mast J, Lugari A, Werle B.
Journal: Vaccine
A steam-based method to investigate biofilm
Authors: Tasse J, Cara A, Saglio M, Villet R, Laurent F.
Journal: Sci Rep.
Biosensors for the Detection of Interaction between Legionella pneumophila Collagen-Like Protein and Glycosaminoglycans
Authors: Su H, Li S, Terebiznik M, Guyard C, Kerman K.
Journal: Sensors (Basel).
A modular transcriptional signature identifies phenotypic heterogeneity of human tuberculosis infection
Authors: Singhania A, Verma R, Graham CM, Lee J, Tran T, Richardson M, Lecine P, Leissner P, Berry MPR, Wilkinson RJ, Kaiser K, Rodrigue M, Woltmann G, Haldar P, O’Garra A.
Journal: Nat Commun.
Small Rho GTPases and the Effector VipA Mediate the Invasion of Epithelial Cells by Filamentous Legionella pneumophila
Authors: Prashar A, Ortiz ME, Lucarelli S, Barker E, Tabatabeiyazdi Z, Shamoun F, Raju D, Antonescu C, Guyard C, Terebiznik MR.
Journal: Front Cell Infect Microbiol.
Culture-free Antibiotic-susceptibility Determination From Single-bacterium Raman Spectra
Authors: Novelli-Rousseau A, Espagnon I, Filiputti D, Gal O, Douet A, Mallard F, Josso Q.
Journal: Sci Rep.
Codon harmonization – going beyond the speed limit for protein expression
Authors: Mignon C, Mariano N, Stadthagen G, Lugari A, Lagoutte P, Donnat S, Chenavas S, Perot C, Sodoyer R, Werle B.
Journal: FEBS Press
Lactobacillus paracasei feeding improves the control of secondary experimental meningococcal infection in flu-infected mice
Authors: Belkacem N, Bourdet-Sicard R, Taha MK.
Journal: BMC Infect Dis.

2017

The human gut microbiome as source of innovation for health: Which physiological and therapeutic outcomes could we expect?
Authors: Doré J, Multon MC, Béhier JM, Affagard H, Andremont A, Barthélémy P, Batitsa R, Bonneville M, Bonny C, Boyaval G, Chamaillard M, Chevalier MP, Cordaillat-Simmons M, Cournarie F, Diaz I, Guillaume E, Guyard C, Jouvin-Marche E, Martin FP, Petiteau D.
Review: Therapie, Elsevier
Modulation of estrogen related receptor alpha activity by the kinesin KIF17.
Authors: Seneviratne APB, Turan Z, Hermant A, Lecine P, Smith WO, Borg JP, Jaulin F, Kreitzer G.
Journal: Oncotarget
Membrane-Active Properties of an Amphitropic Peptide from the CyaA Toxin Translocation Region
Authors: Voegele A, Subrini O, Sapay N, Ladant D, Chenal A.
Journal: Toxins (Basel).
Lactobacillus paracasei feeding improves immune control of influenza infection in mice
Authors: Belkacem N, Serafini N, Wheeler R, Derrien M, Boucinha L, Couesnon A, Cerf-Bensussan N, Gomperts Boneca I, Di Santo JP, Taha MK, Bourdet-Sicard R.
Journal: PLoS One.
Signal management in pharmacovigilance and human risk assessment of CpG 7909, integrating embryo-fetal and post-natal developmental toxicity studies in rats and rabbits
Authors: Delannois F, Planty C, Giordano G, Destexhe E, Stanislaus D, Da Silva FT, Stegmann JU, Thacker K, Reynaud L, Garçon N, Segal L.
Journal: Reprod Toxicol.
Cellular and molecular synergy in AS01-adjuvanted vaccines results in an early IFNγ response promoting vaccine immunogenicity
Authors: Coccia M, Collignon C, Hervé C, Chalon A, Welsby I, Detienne S, Helden MJV, Dutta S, Genito CJ, Waters NC, Deun KV, Smilde AK, Berg RAVD, Franco D, Bourguignon P, Morel S, Garçon N, Lambrecht BN, Goriely S, Most RV, Didierlaurent AM.
Journal: NPJ Vaccines
Different Adjuvants Induce Common Innate Pathways That Are Associated with Enhanced Adaptive Responses against a Model Antigen in Humans
Authors: Burny W, Callegaro A, Bechtold V, Clement F, Delhaye S, Fissette L, Janssens M, Leroux-Roels G, Marchant A, van den Berg R. A, Garçon N, van der Most R and Didierlaurent Arnaud M. On Behalf of the ECR-002 Study Group
Journal: Frontiers in Immunology
The REAnimation Low Immune Status Markers (REALISM) project: a protocol for broad characterisation and follow-up of injury-induced immunosuppression in intensive care unit (ICU) critically ill patients
Authors: Rol ML, Venet F, Rimmele T, Moucadel V, Cortez P, Quemeneur L, Gardiner D, Griffiths A, Pachot A, Textoris J, Monneret G; REALISM study group.
Journal: BMJ Open
Intramuscularly administered herpes zoster subunit vaccine has no effects on fertility, pre- and post-natal development in Sprague-Dawley rats
Authors: Segal L, Thacker K, Fochesato M, Giordano G, Garçon N, Destexhe E.
Journal: Reprod Toxicol.
Type I interferon-mediated autoinflammation due to DNase II deficiency
Authors: Rodero M.P , Tesser A, Bartok E, Rice G. I. , Della Mina E , Depp M, Beitz B, Bondet V, Cagnard N, Duffy D, Dussiot M, Frémond M-L, Gattorno M, Guillem F, Kitabayashi N, Porcheray F, Rieux-Laucat F, Seabra L, Uggenti C, Volpi S, Zeef L.A.H , Alyanakian M-A, Beltrand J, Bianco A-M, Boddaert N, Brouzes C, Candon S, Caorsi R, Charbit M, Fabre M, Faletra F, Girard M, Harroche A, Hartmann E, Lasne D, Marcuzzi A, Neven B, Nitschke P, Pascreau T, Pastore S, Picard C, Picco P,Piscianz E, Polak M, Quartier P, Rabant M, Stocco G, Taddio A, Uettwiller F, Valencic E, Vozzi D, Hartmann G, Barchet W, Hermine O, Bader-Meunier B, Tommasini A & Crow Y.J
Journal: Nature Communication
Respiratory Syncytial Virus Infects Regulatory B Cells in Human Neonates via Chemokine Receptor CX3CR1 and Promotes Lung Disease Severity
Authors: Zhivaki D, Lemoine S, Lim A, Morva A, Vidalain P-O, Schandene L, Casartelli N, Rameix-Welti M-A, Herve P-L , Dériaud E, Beitz B, Ripaux-Lefevre M, Miatello J, Lemercier B, Lorin V, Descamps D, Fix J, Eléouët J-F et Riffault S , Schwartz O, Porcheray F, Mascart F, Mouquet H, Zhang X, Tissières P and Lo-Man R.
Journal: Immunity
Adjuvant system AS01: helping to overcome the challenges of modern vaccines
Authors: Didierlaurent AM, Laupèze B, Di Pasquale A, Hergli N, Collignon C, Garçon N.
Journal: Expert Rev Vaccines
From discovery to licensure, the Adjuvant System story
Authors: Garçon N, Di Pasquale A.
Journal: Hum Vaccin Immunother
Non-conventional expression systems for the production of vaccine proteins and immunotherapeutic molecules
Authors: Legastelois I, Buffin S, Peubez I, Mignon C, Sodoyer R,Werle B
Review: Hum Vaccin & immunotherapeutics
Microbiote intestinal : qu’en attendre au plan physiologique et thérapeutique ?
Authors: Doré J, Multon MC, Béhier JM; les participants à la table ronde 2 des Ateliers de Giens XXXII, Affagard H, Andremont A, Barthélémy P, Batista R, Bonneville M, Bonny C, Boyaval G, Chamaillard M, Chevalier MP, Cordaillat-Simmons M, Cournarie F, Diaz I, Guillaume E, Guyard C, Jouvin-Marche E, Martin FP, Petiteau D.
Journal: Therapie
Clinical, virological, and biological parameters associated with outcomes of Ebola virus infection in Macenta, GuineaAuthors: Vernet MA, Reynard S, Fizet A, Schaeffer J, Pannetier D, Guedj J, Rives M, Georges N, Garcia-Bonnet N, Sylla AI, Grovogui P, Kerherve JY, Savio C, Savio-Coste S, de Séverac ML, Zloczewski P, Linares S, Harouna S, Abdoul BM, Petitjean F, Samake N, Shepherd S, Kinda M, Koundouno FR, Joxe L, Mateo M, Lecine P, Page A, Tchamdja TM, Schoenhals M, Barbe S, Simon B, Tran-Minh T, Longuet C, L’Hériteau F, Baize S.
Journal: JCI Insight Cedratvirus lausannensis – digging into Pithoviridae diversity
Authors: Bertelli C, Mueller L, Thomas V, Pillonel T, Jacquier N, Greub G.
Cedratvirus lausannensis – digging into Pithoviridae diversity.
Bertelli C, Mueller L, Thomas V, Pillonel T, Jacquier N, Greub G.
Environ Microbiol.

2016

SNP calling from RNA-seq data without a reference genome: identification, quantification, differential analysis and impact on the protein sequence
Authors: Lopez-Maestre H, Brinza L, Marchet C, Kielbassa J, Bastien S, Boutigny M, Monnin D, Filali AE, Carareto CM, Vieira C, Picard F, Kremer N, Vavre F, Sagot MF, Lacroix V.
Journal: Nucleic Acids Res.
Chapitre: Les vaccins ou deux siècles de biotechnologies
Authors: Sodoyer R, Drouet E, Werle B
Book: Les biotechnologies en santé tome1.
From discovery to licensure, the Adjuvant System story
Authors: Garçon N, Di Pasquale A.
Journal: Hum Vaccin Immunother.
Vaccine safety evaluation: Practical aspects in assessing benefits and risks
Authors: Di Pasquale A, Bonanni P, Garçon N, Stanberry LR, El-Hodhod M, Tavares Da Silva F.
Journal: Vaccine
Vaccine provision: Delivering sustained & widespread use
Authors: Preiss S, Garçon N, Cunningham AL, Strugnell R, Friedland LR.
Journal: Vaccine
Vaccine development: From concept to early clinical testing
Authors: Cunningham AL, Garçon N, Leo O, Friedland LR, Strugnell R, Laupèze B, Doherty M, Stern P.
Journal: Vaccine
Zika antiviral chemotherapy: identification of drugs and promising starting points for drug discovery from an FDA-approved library
Authors: Pascoalino B.S, Courtemanche G, Cordeiro M.T, Gil L. H. V. G. , Freitas-Junior L
Journal: F1000Research
Impact of adjuvants on CD4(+) T cell and B cell responses to a protein antigen vaccine: Results from a phase II, randomized, multicenter trial
Authors: Leroux-Roels G, Marchant A, Levy J, Van Damme P, Schwarz TF, Horsmans Y, Jilg W, Kremsner PG, Haelterman E, Clément F, Gabor JJ, Esen M, Hens A, Carletti I, Fissette L, Tavares Da Silva F, Burny W, Janssens M, Moris P, Didierlaurent AM, Van Der Most R, Garçon N, Van Belle P, Van Mechelen M.
Journal: Clin Immunol.
Reducing hypoxia and inflammation during invasive pulmonary aspergillosis by targeting the Interleukin-1 receptor
Authors: Gresnigt M.S. , Rekiki A, Rasid O, Savers A, Jouvion G, Dannaoui E, Parlato M, Fitting C, Brock M, Cavaillon J-M, van de Veerdonk F. L. & Ibrahim-Granet O
Journal: Nature Scientific Reports
Chapter 5: Hydrophilic Interaction Liquid Chromatography (HILIC) and Perfluorinated Stationary Phases, pp. 149-184
Authors: Cristina C. JACOB
Book: Fast Liquid Chromatography – Mass Spectrometry Methods in Food and Environmental Analysis (Imperial College Press)
Legionella CRISPR-Cas reveals a recurrent challenge to the pathogen
Authors: Rao C, Guyard C, Pelaz C, Wasserscheid J, Bondy-Denomy J, Dewar K, Ensminger AW.
Journal: Cell Microbiol.
Scalable chromatography-based purification of virus-like particle carrier for epitope based Influenza A vaccine produced in Escherichia coli
Authors: Lagoutte P, Mignon C, Donnat S, Stadthagen G, Mast J, Sodoyer R, Lugari A and Werle B
Journal: J. Virol. Methods
Non-clinical safety evaluation of repeated intramuscular administration of the AS15 immunostimulant combined with various antigens in rabbits and cynomolgus monkeys
Authors: Garçon N, Silvano J, Kuper CF, Baudson N, Gérard C, Forster R, Segal L.
Journal: J Appl Toxicol.

2015

Differential proteomic analysis of virus-enriched fractions obtained from plasma pools of patients with dengue fever or severe dengue
Authors: Fragnoud R, Flamand M, Reynier F, Buchy P, Duong V, Pachot A, Paranhos-Baccala G, Bedin F.
Journal: BMC Infect Dis.
Draft Genome Sequences of Acinetobacter parvus CM11, Acinetobacter radioresistens CM38, and Stenotrophomonas maltophilia BR12, Isolated from Murine Proximal Colonic Tissue
Authors: Saffarian A, Mulet C, Naito T, Bouchier C, Tichit M, Ma L, Grompone G, Sansonetti PJ, Pédron T.
Journal: Genome Announc.
Vaccine Adjuvants: from 1920 to 2015 and BeyondAuthors: Di Pasquale A, Preiss S, Tavares Da Silva F, Garçon N.
Journal: Vaccines
Antibiotic free selection in Biotherapeutics
Authors: Mignon C. , Sodoyer R. , Werle B.
Journal: Antibiotic free selection in Biotherapeutics: Now and Forever, Pathogens
A FACS-optimized screen identifies regulators of genome stability in Candida albicans
Authors: Loll-Krippleber R, Feri A, Nguyen M, Maufrais C, Yansouni J, d’Enfert C, Legrand M
Journal: Eukaryot Cell.
Non clinical reproductive and developmental safety evaluation of he MAGE-A3 Cancer Immunotherapeutic, a therapeutic vaccine for cancer treatment
Authors: Destexhe E, Stannard D, Wilby OK, Grosdidier E, Baudson N, Forster R, Gérard CM, Garçon N, Segal L.
Journal: Elsevier, Reproductive toxicology Volume 51