Publications

Concomitant Assessment of Monocyte HLA-DR Expression and Ex Vivo TNF-α Release as Markers of Adverse OUtcome after Various Injuries – Insights from the REALISM Study
Authors: Frank Bidar, Maxime Bodinier, Fabienne Venet, Anne-Claire Lukaszewicz, Karen Brengel-Pesce, Filippo Conti, Laurence Quemeneur, Philippe Leissner, Lionel K Tan, Julien Textoris, Thomas Rimmelé, Guillaume Monneret, On Behalf Of The Realism Study Group
DOI:10.3390/jcm11010096

Monocyte Trajectories Endotypes Are Associated With Worsening in Septic Patients
Authors: Bodinier M, Peronnet E, Brengel-Pesce K , Conti F, Rimmelé T, Textoris J, Vedrine C,  Quemeneur L, Griffiths A. D., Tan L. K. , Venet F, Maucort-Boulch D, Monneret G, for the REALISM study group
https://doi.org/10.3389/fimmu.2021.795052

COVID-19 vaccine delivery: an opportunity to set up systems for the future
Authors: R. Weintraub, S Plotkin, M Liu,  J Kim, N Garcon, D Bell, D Storisteanu, T Norman, E Aronoff-Spencer 
https://doi.org/10.12688/gatesopenres.13210.2

A standardized gnotobiotic mouse model harboring a minimal 15-member mouse gut microbiota recapitulates SOPF/SPF phenotypes
Authors: Darnaud M, De Vadder F, Bogeat P, Boucinha L, Bulteau A. L, Bunescu A, Couturier C, Delgado A, Dugua H, Elie C, Mathieu A, Novotnà T, Ouattara D. A, Planel S, Saliou A, Srutkova D, Yansouni J, Stecher B, Schwarzer M. , Leulier F, Tamellini A
https://doi.org/10.1038/s41467-021-26963-9

Herpes DNAemia and TTV Viraemia in Intensive Care Unit Critically III patients: A single-Centre Propsective Longitudinal study
Authors: Mallet F, Diouf L,  Meunier B, Perret M,  Reynier F, Leissner P, Quemeneur L ,  Griffiths A.D,  Moucadel V, PachotA , Venet F, Monneret G, Lepape A,  Rimmelé T,  TanL. K,  Brengel-Pesce K and Textoris J  on behalf of the REALISM Study Group
https://doi.org/10.3389/fimmu.2021.698808

Blood transcriptomics reveal the evolution and resolution of the immune response in tuberculosis
Authors: Tabone O, Verma R,  Singhania A, Chakravarty P, Branchett W.J, Graham C.M, Lee J, Trang T, Reynier F, Leissner P, Kaiser K, Rodrigue M, Woltmann G, Haldar P, O’Garra A.
https://doi.org/10.1084/jem.20210915

The antimalarial MMV688533 provides potential for single-dose cures with a high barrier to Plasmodium falciparum parasite resistance
Authors: James M Murithi, Cécile Pascal, Jade Bath, Xavier Boulenc, Nina F Gnädig, Charisse Flerida A Pasaje, Kelly Rubiano, Tomas Yeo, Sachel Mok, Sylvie Klieber, Paul Desert, María Belén Jiménez-Díaz, Jutta Marfurt, Mélanie Rouillier, Mohammed H Cherkaoui-Rbati, Nathalie Gobeau, Sergio Wittlin, Anne-Catrin Uhlemann, Ric N Price, Grennady Wirjanata, Rintis Noviyanti, Patrick Tumwebaze, Roland A Cooper, Philip J Rosenthal, Laura M Sanz, Francisco Javier Gamo, Jayan Joseph, Shivendra Singh, Sridevi Bashyam, Jean Michel Augereau, Elie Giraud, Tanguy Bozec, Thierry Vermat, Gilles Tuffal, Jean-Michel Guillon, Jérôme Menegotto, Laurent Sallé, Guillaume Louit, Marie-José Cabanis, Marie Françoise Nicolas, Michel Doubovetzky, Rita Merino, Nadir Bessila, Iñigo Angulo-Barturen, Delphine Baud, Lidiya Bebrevska, Fanny Escudié, Jacquin C Niles, Benjamin Blasco, Simon Campbell, Gilles Courtemanche, Laurent Fraisse, Alain Pellet, David A Fidock, Didier Leroy
DOI:10.1126/scitranslmed.abg6013

Assessing the Functional Heterogeneity of Monocytes in Human Septic Shock: a Proof-of-Concept Microfluidic Assay of TNFα Secretion 
Authors: Llitjos JF, Bounab Y, Rousseau C, Dixneuf S, Rimbault B, Chiche JF, Textoris J, Pène F. Védrine C.
Front. Immunol., 05 July 2021 | https://doi.org/10.3389/fimmu.2021.686111

Antibody avidity, persistence, and response to antigen recall: comparison of vaccine adjuvants
Authors: Budroni S, Buricchi F, Cavallone A, Bourguignon P, Caubet M, Dewar V, D’Oro U, Finco O, Garçon N, El Idrissi M, Janssens M, Leroux-Roels G, Marchant A, Schwarz T, Van Damme P, Volpini G, van der Most R, Didierlaurent AM, Burny W.
NPJ Vaccines. 2021 May 21;6(1):78. doi: 10.1038/s41541-021-00337-0.

Fast Antibiotic Susceptibility testing via Raman Microspectrometry on Single Bacteria: An MRSA Case study
Authors: Rousseau AN, Faure N, Rol F, Sedaghat Z, Le Galudec J, Mallard F, Josso Q.
ACS Omega. 2021 Jun 15;6(25):16273-16279. doi: 10.1021/acsomega.1c00170

Author Correction: Dynamic single-cell phenotyping of immune cells using the microfluidic platform DropMap
Authors: Bounab Y, Eyer K, Dixneuf S, Rybczynska M, Chauvel C, Mistretta M, Tran T, Aymerich N, Chenon G, Llitjos JF, Venet F, Monneret G, Gillespie IA, Cortez P, Moucadel V, Pachot A, Troesch A, Leissner P, Textoris J, Bibette J, Guyard C, Baudry J, Griffiths AD, Védrine C.
Nat Protoc. 2021 Jan 13. doi: 10.1038/s41596-021-00492-7.

Clinical metagenomics bioinformatics pipeline for the identification of hospital-acquired pneumonia pathogens antibiotic resistance genes form bronchoalveolar lavage samples
Authors:Maud Tournoud, Etienne Ruppé, Guillaume Perrin, Stéphane Schicklin, Ghislaine Guigon, Pierre Mahé, Vladimir Lazarevic, Sébastien Hauser, Caroline Mirande, Albrice Levrat, Karen Louis, Gaspard Gervasi, Jacques Schrenzel
https://doi.org/10.1101/2020.02.26.966309

The impact of the Fungus-Host-Microbiota interplay upon Candida albicans infections: current knowledge and new perspectives.
Authors: d’Enfert C, Kaune AK, Alaban LR, Chakraborty S, Cole N, Delavy M, Kosmala D, Marsaux B, Fróis-Martins R, Morelli M, Rosati D, Valentine M, Xie Z, Emritloll Y, Warn PA, Bequet F, Bougnoux ME, Bornes S, Gresnigt MS, Hube B, Jacobsen ID, Legrand M, Leibundgut-Landmann S, Manichanh C, Munro CA, Netea MG, Queiroz K, Roget K, Thomas V, Thoral C, Van den Abbeele P, Walker AW, Brown AJP.
FEMS Microbiol Rev. 2020 Nov 24:fuaa060. doi: 10.1093/femsre/fuaa060.

 Safety biomarkers for development of vaccines and biologics: Report from the safety biomarkers symposium held on November 28-29, 2017, Marcy l’Etoile, France.
Authors: Doubovetzky M, Ataman-Önal Y, Chousterman B, Feroldi E, Garçon N, Grillet MH, Kramer D, Laurent S, Lewis DJM, Luna E, Manigold T, Syntin P, Burdin N, Fraisse L, Jackson N.Vaccine. 2020 Dec 3;38(51):8055-8063. doi: 10.1016/j.vaccine.2020.10.015.

An integrated transcriptomics and metabolomics study of the immune response of newly hatched chicks to the cytosine-phosphate-guanine oligonucleotide stimulation.
Authors: Ouattara DA, Remolue L, Becker J, Perret M, Bunescu A, Hennig K, Biliaut E, Badin A, Giacomini C, Reynier F, Andreoni C, Béquet F, Lecine P, De Luca K.
Poult Sci. 2020 Sep;99(9):4360-4372. doi: 10.1016/j.psj.2020.06.017.

Draft Genome Sequences of 15 Bacterial Species Constituting the Stable Defined Intestinal Microbiota of the GM15 Gnotobiotic Mouse Model.
Authors: Elie C, Mathieu A, Saliou A, Villain A, Darnaud M, Leulier F, Tamellini A.
Microbiol Resour Announc. 2020 Aug 27;9(35):e00686-20. doi: 10.1128/MRA.00686-20

Caecal microbiota compositions from 7-day-old chicks reared in high-performance and low-performance industrial farms and systematic culturomics to select strains with anti-Campylobacter activity
Authors: Duquenoy A, Ania M, Boucher N, Reynier F, Boucinha L, Andreoni C, Thomas V.
PLoS One. 2020 Aug 24;15(8):e0237541. doi: 10.1371/journal.pone.0237541

Dynamic single-cell phenotyping of immune cells using the microfluidic platform DropMap
Authors: Bounab Y, Eyer K, Dixneuf S, Rybczynska M, Chauvel C, Mistretta M, Tran T, Aymerich N, Chenon G, Llitjos JF, Venet F, Monneret G, Gillespie IA, Cortez P, Moucadel V, Pachot A, Troesch A, Leissner P, Textoris J, Bibette J, Guyard C, Baudry J, Griffiths AD, Védrine C.
Nat Protoc. 2020 Sep;15(9):2920-2955. doi: 10.1038/s41596-020-0354-0

Assessment of Gram- and Viability-Staining Methods for Quantifying Bacterial Community Dynamics Using Flow Cytometry
Duquenoy A, Bellais S, Gasc C, Schwintner C, Dore J, Thomas V.
Front Microbiol. 2020 Jun 26;11:1469. doi: 10.3389/fmicb.2020.01469

The science of vaccine safety: Summary of meeting at Wellcome Trust.
Authors: Plotkin SA, Offit PA, DeStefano F, Larson HJ, Arora NK, Zuber PLF, Fombonne E, Sejvar J, Lambert PH, Hviid A, Halsey N, Garçon N, Peden K, Pollard AJ, Markowitz LE, Glanz J.
Vaccine. 2020 Feb 18;38(8):1869-1880. doi: 10.1016/j.vaccine.2020.01.024

Antibiotic resistance: Tools for effective translational research
Ploy MC, Andremont A, Valtier B, Le Jeunne C; participants of Giens XXXV Round Table ‘Translational research’.Therapie. 2020 Jan-Feb;75(1):7-12. doi: 10.1016/j.therap.2019.12.003. Epub 2019 Dec 16.

Stiffness, pain and joint counts in chronic chikungunya disease: relevance to disability and quality of life
Authors: Watson H., Tritsch S.R. , Encinales L.,  Cadena A. , Cure C., Porras Ramirez A. , Rico Mendoza A., Chang A. Y
Clin Rheumatol. 2020 May;39(5):1679-1686. doi: 10.1007/s10067-019-04919-1

Characterization and analytical validation of a new antigenic rapid diagnostic test for Ebola virus disease detection
Authors: Couturier C, Wada A, Louis K, Mistretta M, Beitz B, Povogui M, Ripaux M, Mignon C, Werle B, Lugari A, Pannetier D, Godard S, Bocquin A, Mely S, Béavogui I, Hébélamou J, Leuenberger D, Leissner P, Yamamoto T, Lécine P, Védrine C, Chaix J.
PLoS Negl Trop Dis. 2020 Jan 17;14(1):e0007965. doi: 10.1371/journal.pntd.0007965

Evaluation of integrative clustering methods for the analysis of multi-omics data
Authors: Chauvel C, Novoloaca A, Veyre P, Reynier F, Becker J
Brief Bioinform. 2020 Feb 14. pii: bbz015. doi: 10.1093/bib/bbz015

Chagas Disease Drug Discovery: Multiparametric Lead Optimization against Trypanosoma cruzi in Acylaminobenzothiazole Series
Authors: Charlotte Fleau, Angel Padilla, Juan Miguel-Siles, Maria T. Quesada-Campos, Isabel Saiz-Nicolas, Ignacio Cotillo, Juan Cantizani Perez, Rick L. Tarleton, Maria Marco and Gilles Courtemanche.
J. Med. Chem. 2019, 62, 10362−10375
https:// pubs.acs.org/jmc

Metagenomic Investigation of Torque Teno Mini Virus-SH in Hematological Patients.
Authors: Bal A, Oriol G, Josset L, Generenaz L, Sarkozy C, Sesques P, Salles G, Morfin F, Lina B, Becker J, Reynier F, Mallet F, Pachot A, Cheynet V, Brengel-Pesce K, Trouillet-Assant S.
Front Microbiol. 2019 Sep 18;10:1898. doi: 10.3389/fmicb.2019.01898.

2HybridTools, a handy software to facilitate clone identification and mutation mapping from yeast two-hybrid screening
Authors: Cauchy P, Kahn-Perlès B, Ferrier P, Imbert J, Lécine P.
PeerJ. 2019 Jul 3;7:e7245. doi: 10.7717/peerj.7245. eCollection 2019.

SATQPCR: Website or statistical analysis of real-timequantitative PCR data
Authors: Rancurel C. , van Tran T., Elie C. , Hilliou F.
Mol Cell Probes, 2019 Aug;46:101418.doi: 10.1016/j.mcp.2019.07.001

Metabolomics, lipidomics and proteomics profiling of myoblasts infected with Trypanosoma cruzi after treatment with different drugs against Chagas disease
Authors: Hennig K., Abi‑Ghanem J., Bunescu A., Meniche X., Biliaut E., Ouattara A. D., Lewis M. D., Kelly J. M., Braillard S., Courtemanche G., Chatelain E., Béquet F.
Metabolomics (2019) 15:117 https://doi.org/10.1007/s11306-019-1583-5

Early herpes and TTV DNAemia in septic shock patients: a pilot study
Authors: Mallet F, Perret M, Tran T, Meunier B, Guichard A, Tabone O, Mommert M, Brengel-Pesce K, Venet F, Pachot A, Monneret G, Reynier F, Védrine C, Leissner P, Mouscadel V, Lepape A, Textoris J, MIPrea Group, REALISM group
Journal Intensive Care Med Exp. 2019

Combination of ribosome display and next generation sequencing as a powerful method for identification of affibody binders against β-lactamase CTX-M15
Authors: Lagoutte P, Lugari A, Elie C, Potisopon S, Donnat S, Mignon C, Mariano N, Troesch A, Werle B, Stadthagen G.;
Journal: N Biotechnol. 2019 May 25;50:60-69

Safety of AS03-adjuvanted influenza vaccines: A review of the evidence.
Authors: Cohet C, van der Most R, Bauchau V, Bekkat-Berkani R, Doherty TM, Schuind A, Tavares Da Silva F, Rappuoli R, Garçon N, Innis BL. Vaccine. 2019

Polymorphisms of a Collagen-Like Adhesin Contributes to Legionella pneumophila Adhesion, Biofilm Formation Capacity and Clinical Prevalence.
Authors: Abdel-Nour M, Su H, Duncan C, Li S, Raju D, Shamoun F, Valton M, Ginevra C, Jarraud S, Guyard C, Kerman K, Terebiznik MR. Front Microbiol. 2019.

Translocation and calmodulin-activation of the adenylate cyclase toxin (CyaA) of Bordetella pertussis
Authors: Voegele A, O’Brien DP, Subrini O, Sapay N, Cannella SE, Enguéné VYN, Hessel A, Karst J, Hourdel V, Perez ACS, Davi M, Veneziano R, Chopineau J, Vachette P, Durand D, Brier S, Ladant D, Chenal A.
Journal: Pathog Dis.

Metagenomics next generation sequencing reveals individual composition and dynamics of anelloviruses during autologous stem cell Transplant Recipient Management
Authors: Bal A, Sarkozy C, Josset L, Cheynet V, Oriol G, Becker J, Vilchez G, Sesques P, Mallet F, Pachot A, Morfin F, Lina B, Salles G, Reynier F, Trouillet-Assant S, Brengel-Pesce K.
Journal: Viruses

Simultaneous surface display and cargo loading of encapsulin nanocompartments and their use for rational vaccine design
Authors: Lagoutte P, Mignon C, Stadthagen G, Potisopon S, Donnat S, Mast J, Lugari A, Werle B.
Journal: Vaccine

A steam-based method to investigate biofilm
Authors: Tasse J, Cara A, Saglio M, Villet R, Laurent F.
Journal: Sci Rep.

Biosensors for the Detection of Interaction between Legionella pneumophila Collagen-Like Protein and Glycosaminoglycans
Authors: Su H, Li S, Terebiznik M, Guyard C, Kerman K.
Journal: Sensors (Basel).

A modular transcriptional signature identifies phenotypic heterogeneity of human tuberculosis infection
Authors: Singhania A, Verma R, Graham CM, Lee J, Tran T, Richardson M, Lecine P, Leissner P, Berry MPR, Wilkinson RJ, Kaiser K, Rodrigue M, Woltmann G, Haldar P, O’Garra A.
Journal: Nat Commun.

Small Rho GTPases and the Effector VipA Mediate the Invasion of Epithelial Cells by Filamentous Legionella pneumophila
Authors: Prashar A, Ortiz ME, Lucarelli S, Barker E, Tabatabeiyazdi Z, Shamoun F, Raju D, Antonescu C, Guyard C, Terebiznik MR.
Journal: Front Cell Infect Microbiol.

Culture-free Antibiotic-susceptibility Determination From Single-bacterium Raman Spectra
Authors: Novelli-Rousseau A, Espagnon I, Filiputti D, Gal O, Douet A, Mallard F, Josso Q.
Journal: Sci Rep.

Codon harmonization – going beyond the speed limit for protein expression
Authors: Mignon C, Mariano N, Stadthagen G, Lugari A, Lagoutte P, Donnat S, Chenavas S, Perot C, Sodoyer R, Werle B.
Journal: FEBS Press

Lactobacillus paracasei feeding improves the control of secondary experimental meningococcal infection in flu-infected mice
Authors: Belkacem N, Bourdet-Sicard R, Taha MK.
Journal: BMC Infect Dis.

The human gut microbiome as source of innovation for health: Which physiological and therapeutic outcomes could we expect?
Authors: Doré J, Multon MC, Béhier JM, Affagard H, Andremont A, Barthélémy P, Batitsa R, Bonneville M, Bonny C, Boyaval G, Chamaillard M, Chevalier MP, Cordaillat-Simmons M, Cournarie F, Diaz I, Guillaume E, Guyard C, Jouvin-Marche E, Martin FP, Petiteau D.
Review: Therapie, Elsevier

Modulation of estrogen related receptor alpha activity by the kinesin KIF17.
Authors: Seneviratne APB, Turan Z, Hermant A, Lecine P, Smith WO, Borg JP, Jaulin F, Kreitzer G.
Journal: Oncotarget

Membrane-Active Properties of an Amphitropic Peptide from the CyaA Toxin Translocation Region
Authors: Voegele A, Subrini O, Sapay N, Ladant D, Chenal A.
Journal: Toxins (Basel).

Lactobacillus paracasei feeding improves immune control of influenza infection in mice
Authors: Belkacem N, Serafini N, Wheeler R, Derrien M, Boucinha L, Couesnon A, Cerf-Bensussan N, Gomperts Boneca I, Di Santo JP, Taha MK, Bourdet-Sicard R.
Journal: PLoS One.

Signal management in pharmacovigilance and human risk assessment of CpG 7909, integrating embryo-fetal and post-natal developmental toxicity studies in rats and rabbits
Authors: Delannois F, Planty C, Giordano G, Destexhe E, Stanislaus D, Da Silva FT, Stegmann JU, Thacker K, Reynaud L, Garçon N, Segal L.
Journal: Reprod Toxicol.

Cellular and molecular synergy in AS01-adjuvanted vaccines results in an early IFNγ response promoting vaccine immunogenicity
Authors: Coccia M, Collignon C, Hervé C, Chalon A, Welsby I, Detienne S, Helden MJV, Dutta S, Genito CJ, Waters NC, Deun KV, Smilde AK, Berg RAVD, Franco D, Bourguignon P, Morel S, Garçon N, Lambrecht BN, Goriely S, Most RV, Didierlaurent AM.
Journal: NPJ Vaccines

Different Adjuvants Induce Common Innate Pathways That Are Associated with Enhanced Adaptive Responses against a Model Antigen in Humans
Authors: Burny W, Callegaro A, Bechtold V, Clement F, Delhaye S, Fissette L, Janssens M, Leroux-Roels G, Marchant A, van den Berg R. A, Garçon N, van der Most R and Didierlaurent Arnaud M. On Behalf of the ECR-002 Study Group
Journal: Frontiers in Immunology

The REAnimation Low Immune Status Markers (REALISM) project: a protocol for broad characterisation and follow-up of injury-induced immunosuppression in intensive care unit (ICU) critically ill patients
Authors: Rol ML, Venet F, Rimmele T, Moucadel V, Cortez P, Quemeneur L, Gardiner D, Griffiths A, Pachot A, Textoris J, Monneret G; REALISM study group.
Journal: BMJ Open

Intramuscularly administered herpes zoster subunit vaccine has no effects on fertility, pre- and post-natal development in Sprague-Dawley rats
Authors: Segal L, Thacker K, Fochesato M, Giordano G, Garçon N, Destexhe E.
Journal: Reprod Toxicol.

Type I interferon-mediated autoinflammation due to DNase II deficiency
Authors: Rodero M.P , Tesser A, Bartok E, Rice G. I. , Della Mina E , Depp M, Beitz B, Bondet V, Cagnard N, Duffy D, Dussiot M, Frémond M-L, Gattorno M, Guillem F, Kitabayashi N, Porcheray F, Rieux-Laucat F, Seabra L, Uggenti C, Volpi S, Zeef L.A.H , Alyanakian M-A, Beltrand J, Bianco A-M, Boddaert N, Brouzes C, Candon S, Caorsi R, Charbit M, Fabre M, Faletra F, Girard M, Harroche A, Hartmann E, Lasne D, Marcuzzi A, Neven B, Nitschke P, Pascreau T, Pastore S, Picard C, Picco P,Piscianz E, Polak M, Quartier P, Rabant M, Stocco G, Taddio A, Uettwiller F, Valencic E, Vozzi D, Hartmann G, Barchet W, Hermine O, Bader-Meunier B, Tommasini A & Crow Y.J
Journal: Nature Communication

Respiratory Syncytial Virus Infects Regulatory B Cells in Human Neonates via Chemokine Receptor CX3CR1 and Promotes Lung Disease Severity
Authors: Zhivaki D, Lemoine S, Lim A, Morva A, Vidalain P-O, Schandene L, Casartelli N, Rameix-Welti M-A, Herve P-L , Dériaud E, Beitz B, Ripaux-Lefevre M, Miatello J, Lemercier B, Lorin V, Descamps D, Fix J, Eléouët J-F et Riffault S , Schwartz O, Porcheray F, Mascart F, Mouquet H, Zhang X, Tissières P and Lo-Man R.
Journal: Immunity

Adjuvant system AS01: helping to overcome the challenges of modern vaccines
Authors: Didierlaurent AM, Laupèze B, Di Pasquale A, Hergli N, Collignon C, Garçon N.
Journal: Expert Rev Vaccines

From discovery to licensure, the Adjuvant System story
Authors: Garçon N, Di Pasquale A.
Journal: Hum Vaccin Immunother

Non-conventional expression systems for the production of vaccine proteins and immunotherapeutic molecules
Authors: Legastelois I, Buffin S, Peubez I, Mignon C, Sodoyer R,Werle B
Review: Hum Vaccin & immunotherapeutics

Clinical, virological, and biological parameters associated with outcomes of Ebola virus infection in Macenta, Guinea
Authors: Vernet MA, Reynard S, Fizet A, Schaeffer J, Pannetier D, Guedj J, Rives M, Georges N, Garcia-Bonnet N, Sylla AI, Grovogui P, Kerherve JY, Savio C, Savio-Coste S, de Séverac ML, Zloczewski P, Linares S, Harouna S, Abdoul BM, Petitjean F, Samake N, Shepherd S, Kinda M, Koundouno FR, Joxe L, Mateo M, Lecine P, Page A, Tchamdja TM, Schoenhals M, Barbe S, Simon B, Tran-Minh T, Longuet C, L’Hériteau F, Baize S.
Journal: JCI Insight Cedratvirus lausannensis – digging into Pithoviridae diversity
Authors: Bertelli C, Mueller L, Thomas V, Pillonel T, Jacquier N, Greub G.

Cedratvirus lausannensis – digging into Pithoviridae diversity.
Bertelli C, Mueller L, Thomas V, Pillonel T, Jacquier N, Greub G.
Environ Microbiol.

SNP calling from RNA-seq data without a reference genome: identification, quantification, differential analysis and impact on the protein sequence
Authors: Lopez-Maestre H, Brinza L, Marchet C, Kielbassa J, Bastien S, Boutigny M, Monnin D, Filali AE, Carareto CM, Vieira C, Picard F, Kremer N, Vavre F, Sagot MF, Lacroix V.
Journal: Nucleic Acids Res.

Chapitre: Les vaccins ou deux siècles de biotechnologies
Authors: Sodoyer R, Drouet E, Werle B
Book: Les biotechnologies en santé tome1.

From discovery to licensure, the Adjuvant System story
Authors: Garçon N, Di Pasquale A.
Journal: Hum Vaccin Immunother.

Vaccine safety evaluation: Practical aspects in assessing benefits and risks
Authors: Di Pasquale A, Bonanni P, Garçon N, Stanberry LR, El-Hodhod M, Tavares Da Silva F.
Journal: Vaccine

Vaccine provision: Delivering sustained & widespread use
Authors: Preiss S, Garçon N, Cunningham AL, Strugnell R, Friedland LR.
Journal: Vaccine

Vaccine development: From concept to early clinical testing
Authors: Cunningham AL, Garçon N, Leo O, Friedland LR, Strugnell R, Laupèze B, Doherty M, Stern P.
Journal: Vaccine

Zika antiviral chemotherapy: identification of drugs and promising starting points for drug discovery from an FDA-approved library
Authors: Pascoalino B.S, Courtemanche G, Cordeiro M.T, Gil L. H. V. G. , Freitas-Junior L
Journal: F1000Research

Impact of adjuvants on CD4(+) T cell and B cell responses to a protein antigen vaccine: Results from a phase II, randomized, multicenter trial
Authors: Leroux-Roels G, Marchant A, Levy J, Van Damme P, Schwarz TF, Horsmans Y, Jilg W, Kremsner PG, Haelterman E, Clément F, Gabor JJ, Esen M, Hens A, Carletti I, Fissette L, Tavares Da Silva F, Burny W, Janssens M, Moris P, Didierlaurent AM, Van Der Most R, Garçon N, Van Belle P, Van Mechelen M.
Journal: Clin Immunol.

Reducing hypoxia and inflammation during invasive pulmonary aspergillosis by targeting the Interleukin-1 receptor
Authors: Gresnigt M.S. , Rekiki A, Rasid O, Savers A, Jouvion G, Dannaoui E, Parlato M, Fitting C, Brock M, Cavaillon J-M, van de Veerdonk F. L. & Ibrahim-Granet O
Journal: Nature Scientific Reports

Chapter 5: Hydrophilic Interaction Liquid Chromatography (HILIC) and Perfluorinated Stationary Phases, pp. 149-184
Authors: Cristina C. JACOB
Book: Fast Liquid Chromatography – Mass Spectrometry Methods in Food and Environmental Analysis (Imperial College Press)

Legionella CRISPR-Cas reveals a recurrent challenge to the pathogen
Authors: Rao C, Guyard C, Pelaz C, Wasserscheid J, Bondy-Denomy J, Dewar K, Ensminger AW.
Journal: Cell Microbiol.

Scalable chromatography-based purification of virus-like particle carrier for epitope based Influenza A vaccine produced in Escherichia coli
Authors: Lagoutte P, Mignon C, Donnat S, Stadthagen G, Mast J, Sodoyer R, Lugari A and Werle B
Journal: J. Virol. Methods

Non-clinical safety evaluation of repeated intramuscular administration of the AS15 immunostimulant combined with various antigens in rabbits and cynomolgus monkeys
Authors: Garçon N, Silvano J, Kuper CF, Baudson N, Gérard C, Forster R, Segal L.
Journal: J Appl Toxicol.

Differential proteomic analysis of virus-enriched fractions obtained from plasma pools of patients with dengue fever or severe dengue
Authors: Fragnoud R, Flamand M, Reynier F, Buchy P, Duong V, Pachot A, Paranhos-Baccala G, Bedin F.
Journal: BMC Infect Dis.

Draft Genome Sequences of Acinetobacter parvus CM11, Acinetobacter radioresistens CM38, and Stenotrophomonas maltophilia BR12, Isolated from Murine Proximal Colonic Tissue
Authors: Saffarian A, Mulet C, Naito T, Bouchier C, Tichit M, Ma L, Grompone G, Sansonetti PJ, Pédron T.
Journal: Genome Announc.

Vaccine Adjuvants: from 1920 to 2015 and Beyond
Authors: Di Pasquale A, Preiss S, Tavares Da Silva F, Garçon N.
Journal: Vaccines

Antibiotic free selection in Biotherapeutics
Authors: Mignon C. , Sodoyer R. , Werle B.
Journal: Antibiotic free selection in Biotherapeutics: Now and Forever, Pathogens

A FACS-optimized screen identifies regulators of genome stability in Candida albicans
Authors: Loll-Krippleber R, Feri A, Nguyen M, Maufrais C, Yansouni J, d’Enfert C, Legrand M
Journal: Eukaryot Cell.

Non clinical reproductive and developmental safety evaluation of he MAGE-A3 Cancer Immunotherapeutic, a therapeutic vaccine for cancer treatment
Authors: Destexhe E, Stannard D, Wilby OK, Grosdidier E, Baudson N, Forster R, Gérard CM, Garçon N, Segal L.
Journal: Elsevier, Reproductive toxicology Volume 51